rs1421085(C;T)

~1.3x increased obesity risk

Magnitude
2.5Worth knowing
Repute
Bad
Frequency
29%Average of 11 populations
On SNPedia
rs1421085(C;T)
Gene
FTO

Frequency

Share of people with C;T in each HapMap population.

  • European ancestry (Utah)53%
  • Tuscan44%
  • Gujarati Indian42%
  • Mexican ancestry (Los Angeles)35%
  • Japanese (Tokyo)31%
  • Chinese (Denver)25%
  • Maasai (Kenya)25%
  • Han Chinese (Beijing)23%
  • African ancestry (Southwest US)21%
  • Yoruba (Nigeria)12%
  • Luhya (Kenya)4%

Other genotypes of rs1421085

  1. C;CMost notableBad~1.7x increased obesity riskImportant · 3.16% of people
  2. T;TGoodnormal obesity riskTypical · 0.166% of people

All about rs1421085

Source and license

Adapted from rs1421085(C;T) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.