rs1426310

A SNP in the DSG1 gene on chromosome 18. Its most notable genotype is A;A: common in clinvar

Gene
DSG1
Location
Chr 1831,318,331 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
35%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AMost notableGoodcommon in clinvarTypical · 0.049% of people
  2. A;GNot ratedNo summary available.Typical · 0.038% of people

On SNPedia: (A;A), (A;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageA;A 49% A;G 38%
  • European ancestry (Utah)A;A 26% A;G 58%
  • Han Chinese (Beijing)A;A 90% A;G 10%
  • Japanese (Tokyo)A;A 86% A;G 14%
  • Yoruba (Nigeria)A;A 25% A;G 50%
  • African ancestry (Southwest US)A;A 32% A;G 51%
  • Chinese (Denver)A;A 89% A;G 11%
  • Gujarati IndianA;A 26% A;G 53%
  • Luhya (Kenya)A;A 46% A;G 43%
  • Mexican ancestry (Los Angeles)A;A 59% A;G 36%
  • Maasai (Kenya)A;A 38% A;G 50%
  • TuscanA;A 28% A;G 47%

Other DSG1 SNPs

All DSG1 SNPs

Source and license

Adapted from rs1426310 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.