rs143334143

A SNP. Its most notable genotype is A;G: Higher (1.9x) risk for COVID-19 illness being severe

Gene
None listed
Highest magnitude
1.9Minor
Tested on
Not on consumer chips

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;GMost notableBadHigher (1.9x) risk for COVID-19 illness being severeMinor · 1.9
  2. G;GGoodcommon/normalTypical · 0.0

On SNPedia: (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Notes

From SNPedia

Notes

Genetic mechanisms of critical illness in Covid-19 nature.com; moderate increase (1.9x) for risk of becoming critically ill upon COVID-19 infection for carriers of the minor (A) allele Note this SNP is tightly linked to, and presumably reflecting the same risk factor as two SNPs that are commonly found on DNA chips used by companies such as MyHeritage or Ancestry, rs130072 and also rs2073724; in the FWD (plus) orientation, the minor alleles for those SNPs are both T (and the major, non-risk allele is C).

A;G

see text on main rs-page

Source and license

Adapted from rs143334143 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.