rs1446109

A SNP in the CTNNA2 gene on chromosome 2. Its most notable genotype is A;A.

Gene
CTNNA2
Location
Chr 280,311,294 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
16%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AMost notableNot ratedNo summary available.Typical · 0.074% of people

On SNPedia: (A;A). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageA;A 74%
  • European ancestry (Utah)A;A 74%
  • Han Chinese (Beijing)A;A 50%
  • Japanese (Tokyo)A;A 37%
  • Yoruba (Nigeria)A;A 80%
  • African ancestry (Southwest US)A;A 88%
  • Chinese (Denver)A;A 62%
  • Gujarati IndianA;A 90%
  • Luhya (Kenya)A;A 90%
  • Mexican ancestry (Los Angeles)A;A 69%
  • Maasai (Kenya)A;A 85%
  • TuscanA;A 88%

Conditions, medicines and genes

Genosets

Genosets combine several genotypes. Twofold checks them in your report.

Notes

From SNPedia

Notes

having minor alleles at all 3 of rs1446109-rs1007371-rs723524 may affect left-right asymmetrical brain function, such as handedness, and much of human cognition, behavior and emotion. pdf full paper Genome-wide association and meta-analysis of bipolar disorder in individuals of European ancestry.

Source and license

Adapted from rs1446109 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.