rs1446109
A SNP in the CTNNA2 gene on chromosome 2. Its most notable genotype is A;A.
- Gene
- CTNNA2
- Location
- Chr 280,311,294 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
- Minor allele frequency
- 16%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (A;A). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageA;A 74%
- European ancestry (Utah)A;A 74%
- Han Chinese (Beijing)A;A 50%
- Japanese (Tokyo)A;A 37%
- Yoruba (Nigeria)A;A 80%
- African ancestry (Southwest US)A;A 88%
- Chinese (Denver)A;A 62%
- Gujarati IndianA;A 90%
- Luhya (Kenya)A;A 90%
- Mexican ancestry (Los Angeles)A;A 69%
- Maasai (Kenya)A;A 85%
- TuscanA;A 88%
Related
Conditions, medicines and genes
Genosets
Genosets combine several genotypes. Twofold checks them in your report.
Notes
From SNPedia
Notes
having minor alleles at all 3 of rs1446109-rs1007371-rs723524 may affect left-right asymmetrical brain function, such as handedness, and much of human cognition, behavior and emotion. pdf full paper Genome-wide association and meta-analysis of bipolar disorder in individuals of European ancestry.
Source and license
Adapted from rs1446109 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.