rs1466535

A SNP in the LRP1 gene on chromosome 12. Its most notable genotype is G;G: common/normal

Gene
LRP1
Location
Chr 1257,140,687 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe
Minor allele frequency
27%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. G;GMost notableGoodcommon/normalTypical · 0.058% of people

SNPedia records rs1466535 on the minus strand: (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageG;G 58%
  • European ancestry (Utah)G;G 46%
  • Han Chinese (Beijing)G;G 64%
  • Japanese (Tokyo)G;G 66%
  • Yoruba (Nigeria)G;G 66%
  • African ancestry (Southwest US)G;G 67%
  • Chinese (Denver)G;G 61%
  • Gujarati IndianG;G 32%
  • Luhya (Kenya)G;G 76%
  • Mexican ancestry (Los Angeles)G;G 35%
  • Maasai (Kenya)G;G 78%
  • TuscanG;G 48%

Other LRP1 SNPs

All LRP1 SNPs

Source and license

Adapted from rs1466535 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.