rs150074056

A SNP in the FUT1 gene on chromosome 19. Its most notable genotype is A;A: Para-Bombay phenotype (blood transfusion consequences)

Gene
FUT1
Location
Chr 1948,750,933 (GRCh38)
Highest magnitude
2.0Worth knowing
Tested on
AncestryDNA

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AMost notableBadPara-Bombay phenotype (blood transfusion consequences)Worth knowing · 2.0
  2. A;GNot ratedCarrier of a Para-Bombay phenotype (blood transfusion consequence)Worth knowing · 2.0
  3. G;GGoodcommon in clinvarTypical · 0.0

On SNPedia: (A;A), (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Other FUT1 SNPs

All FUT1 SNPs

Notes

From SNPedia

Notes

aka c.349C>T (p.His117Tyr) FUT1 Para-Bombay phenotype; according to OMIM, this mutation is responsible for the weak H-deficient Reunion variant (when homozygous). Note: Bombay and para-Bombay individuals display no apparent deleterious phenotype except in circumstances requiring blood transfusion, where they are cross-match incompatible with all donors except other H-deficient individuals. 23andMe name: i709466

A;A

see text and links via main rs-page

A;G

Unaffected in absence of a second FUT1 gene mutation; see text on main rs-page

Source and license

Adapted from rs150074056 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.