rs1516446
A SNP in the COL3A1 gene on chromosome 2. Its most notable genotype is G;G: common in complete genomics
- Gene
- COL3A1
- Location
- Chr 2189,010,695 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
- Minor allele frequency
- <1%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (G;G), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 6 HapMap populations.
- AverageG;G 98% T;T <1%
- European ancestry (Utah)G;G 100% T;T 0%
- Han Chinese (Beijing)G;G 99% T;T 0%
- Japanese (Tokyo)G;G 99% T;T 0%
- Yoruba (Nigeria)G;G 97% T;T <1%
- Luhya (Kenya)G;G 95% T;T 0%
- Maasai (Kenya)G;G 98% T;T 0%
Related
Other COL3A1 SNPs
- rs111505097A;GEhlers-Danlos Syndrome (EDS) type 4Very important
- rs111929073G;TEhlers-Danlos Syndrome (EDS) type 4Very important
- rs112371422C;TEhlers-Danlos Syndrome (EDS) type 4Very important
- rs112456072A;GEhlers-Danlos Syndrome (EDS) type 4Very important
- rs113485686A;GEhlers-Danlos Syndrome (EDS) type 4Very important
- rs113871730A;GEhlers-Danlos Syndrome (EDS) type 4Very important
- rs121912913G;TEhlers-Danlos Syndrome (EDS) type 4Very important
- rs121912914A;GEhlers-Danlos Syndrome (EDS) type 4Very important
Source and license
Adapted from rs1516446 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.