rs1601012

A SNP in the SCN8A gene on chromosome 12. Its most notable genotype is A;A: possible decreased suicide risk

Gene
SCN8A
Location
Chr 1251,685,722 (GRCh38)
Highest magnitude
1.0Minor
Tested on
23andMe
Minor allele frequency
28%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AMost notableGoodpossible decreased suicide riskMinor · 1.015% of people
  2. C;CNot ratednormal suicide riskMinor · 1.051% of people

On SNPedia: (A;A), (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 4 HapMap populations.

  • AverageA;A 15% C;C 51%
  • European ancestry (Utah)A;A 0% C;C 63%
  • Han Chinese (Beijing)A;A 4% C;C 62%
  • Japanese (Tokyo)A;A 2% C;C 68%
  • Yoruba (Nigeria)A;A 54% C;C 11%

Other SCN8A SNPs

All SCN8A SNPs

Notes

From SNPedia

Notes

Genetic polymorphisms in the SCN8A gene are associated with suicidal behavior in psychiatric disorders in the Chinese population.

A;A

See Genetic polymorphisms in the SCN8A gene are associated with suicidal behavior in psychiatric disorders in the Chinese population

C;C

See Genetic polymorphisms in the SCN8A gene are associated with suicidal behavior in psychiatric disorders in the Chinese population

Source and license

Adapted from rs1601012 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.