rs1613662
A SNP in the GP6 gene on chromosome 19. Its most notable genotype is A;A: common in complete genomics
- Gene
- GP6
- Location
- Chr 1955,025,227 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
- Minor allele frequency
- 13%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (A;A), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageA;A 72% G;G 4%
- European ancestry (Utah)A;A 68% G;G 6%
- Han Chinese (Beijing)A;A 97% G;G 0%
- Japanese (Tokyo)A;A 98% G;G 0%
- Yoruba (Nigeria)A;A 59% G;G 5%
- African ancestry (Southwest US)A;A 63% G;G 7%
- Chinese (Denver)A;A 97% G;G 0%
- Gujarati IndianA;A 53% G;G 6%
- Luhya (Kenya)A;A 56% G;G 10%
- Mexican ancestry (Los Angeles)A;A 86% G;G 2%
- Maasai (Kenya)A;A 52% G;G 5%
- TuscanA;A 66% G;G 2%
Related
Conditions, medicines and genes
Notes
From SNPedia
Show notes, about 190 words
Gene variants associated with deep vein thrombosis. Updated analysis of gene variants associated with deep vein thrombosis. per risk allele odds ratio *rs13146272 in CYP4V2 (risk allele frequency, 0.64) OR 1.24 (95% CI, 1.11-1.37) for rs13146272 *rs2227589 in SERPINC1 (risk allele frequency, 0.10) OR 1.29 (95% CI, 1.10-1.49) for rs2227589 *rs1613662 in GP6 (risk allele frequency, 0.84) OR 1.15 (95% CI, 1.01-1.30) for rs1613662 A study of 453 VTE cases and 1,327 controls was able to replicate the "mild effects" of this SNP on risk for VTE, however they felt that stronger associations were found between increased VTE risk and either the Factor V Leiden mutation (rs6025)or having blood types O or A2. An evaluation of candidate genes of inflammation and thrombosis in relation to the risk of venous thromboembolism: The Women's Genome Health Study. New gene variants associated with venous thrombosis: a replication study in White and Black Americans. Genetic determinants of platelet reactivity during acetylsalicylic acid therapy in diabetic patients: evaluation of 27 polymorphisms within candidate genes.
Source and license
Adapted from rs1613662 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.