rs1621
A SNP in the MET gene on chromosome 7. Its most notable genotype is G;G: common in clinvar
- Gene
- MET
- Location
- Chr 7116,797,552 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
- Minor allele frequency
- 30%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageG;G 11%
- European ancestry (Utah)G;G 8%
- Han Chinese (Beijing)G;G <1%
- Japanese (Tokyo)G;G 3%
- Yoruba (Nigeria)G;G 24%
- African ancestry (Southwest US)G;G 19%
- Chinese (Denver)G;G 3%
- Gujarati IndianG;G 4%
- Luhya (Kenya)G;G 25%
- Mexican ancestry (Los Angeles)G;G 11%
- Maasai (Kenya)G;G 12%
- TuscanG;G 11%
Related
Other MET SNPs
- rs121913243A;GFamilial papillary renal cell carcinomaVery important
- rs121913668C;TFamilial papillary renal cell carcinomaVery important
- rs121913670A;GFamilial papillary renal cell carcinomaVery important
- rs786202724A;GFamilial papillary renal cell carcinomaVery important
- rs2237717T;Treduced abilities related to neurocognition and ability to recognize facesImportant
- rs1858830C;C2x risk of autism reported by some (but not other) publicationsWorth knowing
- rs6566G;Gcommon in clinvarTypical
Source and license
Adapted from rs1621 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.