rs1642742
A SNP in the VHL gene on chromosome 3. Its most notable genotype is G;G: common in clinvar
- Gene
- VHL
- Location
- Chr 310,150,259 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
SNPedia records rs1642742 on the minus strand: (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageG;G 28%
- European ancestry (Utah)G;G 10%
- Han Chinese (Beijing)G;G 4%
- Japanese (Tokyo)G;G 11%
- Yoruba (Nigeria)G;G 63%
- African ancestry (Southwest US)G;G 47%
- Chinese (Denver)G;G 6%
- Gujarati IndianG;G 15%
- Luhya (Kenya)G;G 66%
- Mexican ancestry (Los Angeles)G;G 17%
- Maasai (Kenya)G;G 55%
- TuscanG;G 11%
Related
Other VHL SNPs
- rs5030802A;GVon Hippel-Lindau syndrome mutationVery important
- rs5030804A;CVon Hippel-Lindau syndrome mutationVery important
- rs5030807A;TVon Hippel-Lindau syndrome mutationVery important
- rs5030808A;GVon Hippel-Lindau syndrome mutationVery important
- rs5030809C;TVon Hippel-Lindau syndrome mutationVery important
- rs5030810C;TVon Hippel-Lindau syndrome mutationVery important
- rs5030812A;CVon Hippel-Lindau syndrome mutationVery important
- rs5030813C;TVon Hippel-Lindau syndrome mutationVery important
Source and license
Adapted from rs1642742 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.