rs1667255

A SNP on chromosome 18. Its most notable genotype is A;A: decrease circulating retinol levels

Gene
None listed
Location
Chr 1831,607,316 (GRCh38)
Highest magnitude
1.0Minor
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
46%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AMost notableBaddecrease circulating retinol levelsMinor · 1.025% of people
  2. A;CGoodincrease circulating retinol levels.Minor · 1.045% of people
  3. C;CGoodincrease circulating retinol levels.Minor · 1.030% of people

On SNPedia: (A;A), (A;C), (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageA;A 25% A;C 45% C;C 30%
  • European ancestry (Utah)A;A 46% A;C 43% C;C 11%
  • Han Chinese (Beijing)A;A 40% A;C 41% C;C 19%
  • Japanese (Tokyo)A;A 49% A;C 43% C;C 8%
  • Yoruba (Nigeria)A;A 3% A;C 38% C;C 59%
  • African ancestry (Southwest US)A;A 14% A;C 44% C;C 42%
  • Chinese (Denver)A;A 33% A;C 48% C;C 19%
  • Gujarati IndianA;A 23% A;C 57% C;C 20%
  • Luhya (Kenya)A;A 6% A;C 27% C;C 67%
  • Mexican ancestry (Los Angeles)A;A 28% A;C 60% C;C 12%
  • Maasai (Kenya)A;A 9% A;C 42% C;C 49%
  • TuscanA;A 28% A;C 49% C;C 24%

Source and license

Adapted from rs1667255 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.