rs16853571
A SNP in the LOC105374425 gene on chromosome 4. Its most notable genotype is A;A: common in complete genomics
- Gene
- LOC105374425
- Location
- Chr 441,751,113 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
- Minor allele frequency
- 7%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (A;A). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 10 HapMap populations.
- AverageA;A 82%
- European ancestry (Utah)A;A 87%
- Han Chinese (Beijing)A;A 99%
- Japanese (Tokyo)A;A 100%
- Yoruba (Nigeria)A;A 65%
- African ancestry (Southwest US)A;A 65%
- Gujarati IndianA;A 73%
- Luhya (Kenya)A;A 65%
- Mexican ancestry (Los Angeles)A;A 98%
- Maasai (Kenya)A;A 76%
- TuscanA;A 92%
Notes
From SNPedia
Notes
rs16853571 increases susceptibility to Crohn's disease 1.45 times for carriers of the A allele
Source and license
Adapted from rs16853571 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.