rs16879765

A SNP in the EPDR1 gene on chromosome 7. Its most notable genotype is T;T: Somewhat higher (~3x) risk for Dupuytren's Disease

Gene
EPDR1
Location
Chr 737,949,493 (GRCh38)
Highest magnitude
3.0Important
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
12%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;CGoodcommon in complete genomicsTypical · 0.079% of people
  2. C;TBadSomewhat higher (~2x) risk for Dupuytren's DiseaseWorth knowing · 2.020% of people
  3. T;TMost notableBadSomewhat higher (~3x) risk for Dupuytren's DiseaseImportant · 3.01% of people

On SNPedia: (C;C), (C;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageC;C 79% C;T 20% T;T 1%
  • European ancestry (Utah)C;C 91% C;T 9% T;T 0%
  • Han Chinese (Beijing)C;C 80% C;T 19% T;T <1%
  • Japanese (Tokyo)C;C 83% C;T 17% T;T 0%
  • Yoruba (Nigeria)C;C 67% C;T 27% T;T 6%
  • African ancestry (Southwest US)C;C 67% C;T 32% T;T 2%
  • Chinese (Denver)C;C 86% C;T 13% T;T <1%
  • Gujarati IndianC;C 66% C;T 31% T;T 3%
  • Luhya (Kenya)C;C 73% C;T 27% T;T 0%
  • Mexican ancestry (Los Angeles)C;C 79% C;T 21% T;T 0%
  • Maasai (Kenya)C;C 87% C;T 13% T;T 0%
  • TuscanC;C 84% C;T 16% T;T 0%

Notes

From SNPedia

Notes

C;T

see discussion at Dupuytren's disease

T;T

see discussion at Dupuytren's disease

Source and license

Adapted from rs16879765 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.