rs16940342
A SNP in the PALB2 gene on chromosome 16. Its most notable genotype is A;A: common in clinvar
- Gene
- PALB2
- Location
- Chr 1623,633,265 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
- Minor allele frequency
- 19%
Genotypes
As shown in 23andMe and AncestryDNA files.
- A;AMost notableGoodcommon in clinvar
- A;GNot ratedConsidered benign according to ClinVar
- G;GNot ratedConsidered benign according to ClinVar
On SNPedia: (A;A), (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageA;A 64% A;G 32% G;G 5%
- European ancestry (Utah)A;A 80% A;G 20% G;G <1%
- Han Chinese (Beijing)A;A 58% A;G 37% G;G 5%
- Japanese (Tokyo)A;A 65% A;G 33% G;G 3%
- Yoruba (Nigeria)A;A 63% A;G 31% G;G 7%
- African ancestry (Southwest US)A;A 65% A;G 28% G;G 7%
- Chinese (Denver)A;A 60% A;G 38% G;G 3%
- Gujarati IndianA;A 65% A;G 30% G;G 5%
- Luhya (Kenya)A;A 60% A;G 36% G;G 5%
- Mexican ancestry (Los Angeles)A;A 66% A;G 31% G;G 3%
- Maasai (Kenya)A;A 41% A;G 48% G;G 11%
- TuscanA;A 79% A;G 20% G;G 1%
Related
Other PALB2 SNPs
- rs118203997T;TFanconi anemia, complementation group NVery important
- rs118203998C;CFanconi anemia, complementation group NVery important
- rs118203999A;AFanconi anemia, complementation group NVery important
- rs180177083A;AFanconi anemia, complementation group NVery important
- rs180177084-;-Fanconi anemia, complementation group NVery important
- rs180177085-;-Fanconi anemia, complementation group NVery important
- rs180177090-;-Fanconi anemia, complementation group NVery important
- rs180177091A;AFanconi anemia, complementation group NVery important
Source and license
Adapted from rs16940342 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.