rs17107315

A SNP in the SPINK1 gene on chromosome 5. Its most notable genotype is G;G: risk of pancreatitis

Gene
SPINK1
Location
Chr 5147,828,115 (GRCh38)
Highest magnitude
4.0Very important
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
<1%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. T;TGoodcommon genotypeTypical · 0.00% of people
  2. G;GMost notableBadrisk of pancreatitisVery important · 4.00% of people
  3. A;GBadrisk of pancreatitisImportant · 3.02% of people
  4. A;AGoodnormalTypical · 0.098% of people

SNPedia records rs17107315 on the minus strand: (A;A), (C;C), (C;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 7 HapMap populations.

  • AverageT;T 0% G;G 0% A;G 2% A;A 98%
  • European ancestry (Utah)T;T 0% G;G 0% A;G <1% A;A 99%
  • Han Chinese (Beijing)T;T 0% G;G 0% A;G 2% A;A 99%
  • Japanese (Tokyo)T;T 0% G;G 0% A;G 4% A;A 97%
  • Yoruba (Nigeria)T;T 0% G;G 0% A;G 0% A;A 100%
  • Chinese (Denver)T;T 0% G;G 0% A;G <1% A;A 99%
  • Gujarati IndianT;T 0% G;G 0% A;G 3% A;A 97%
  • TuscanT;T 0% G;G 0% A;G 2% A;A 98%

Source and license

Adapted from rs17107315 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.