rs1711437(C;C)
Slightly reduced creatinine clearance
- Magnitude
- 2.4Worth knowing
- Repute
- Bad
- Frequency
- 40%Average of 11 populations
- On SNPedia
- rs1711437(G;G)Minus strand
- Gene
- MMP20
Frequency
Share of people with C;C in each HapMap population.
- Yoruba (Nigeria)59%
- Luhya (Kenya)56%
- African ancestry (Southwest US)51%
- Maasai (Kenya)43%
- Japanese (Tokyo)43%
- Chinese (Denver)40%
- Han Chinese (Beijing)38%
- European ancestry (Utah)35%
- Tuscan30%
- Mexican ancestry (Los Angeles)26%
- Gujarati Indian25%
Other genotypes of rs1711437
Notes
From SNPedia
In the BLSA population, the genotype of rs1711437 explains 2.1% of the variation in creatinine clearance and in the InCHIANTI population, the genotype explains 0.9% of the variation. G is the risk allele. For an individual who carries two copies of the G allele, his or her creatinine clearance is approximately that of someone 4–5 years older who carries no G alleles. The association between rs1711437 genotype and creatinine clearance has not been replicated in additional populations.
Source and license
Adapted from rs1711437(G;G) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.