rs17145738

A SNP in the TBL2 gene on chromosome 7. Its most notable genotype is C;C: common on affy axiom data

Gene
TBL2
Location
Chr 773,568,544 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA
Minor allele frequency
10%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;CMost notableGoodcommon on affy axiom dataTypical · 0.082% of people

On SNPedia: (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageC;C 82%
  • European ancestry (Utah)C;C 78%
  • Han Chinese (Beijing)C;C 73%
  • Japanese (Tokyo)C;C 81%
  • Yoruba (Nigeria)C;C 82%
  • African ancestry (Southwest US)C;C 88%
  • Chinese (Denver)C;C 83%
  • Gujarati IndianC;C 88%
  • Luhya (Kenya)C;C 84%
  • Mexican ancestry (Los Angeles)C;C 83%
  • Maasai (Kenya)C;C 80%
  • TuscanC;C 84%

Conditions, medicines and genes

Notes

From SNPedia

Notes

rs17145738 influences severe hypertriglyceridemia. 132 patients of European ancestry with severe HTG (fasting plasma TG>10 mmol/L), and 351 matched normolipidemic controls

Source and license

Adapted from rs17145738 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.