rs17173608

A SNP in the RARRES2 gene on chromosome 7. Its most notable genotype is G;G: lower visceral adipose tissue

Gene: RARRES2
Location: Chr 7150,339,575 (GRCh38)
Highest magnitude: 0.0Typical
Tested on: 23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency: 9%

Genotypes

As shown in 23andMe and AncestryDNA files.

On SNPedia: (G;G), (G;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

AverageG;G 2% G;T 21% T;T 77%
European ancestry (Utah)G;G 0% G;T 10% T;T 90%
Han Chinese (Beijing)G;G 0% G;T 8% T;T 92%
Japanese (Tokyo)G;G <1% G;T 9% T;T 90%
Yoruba (Nigeria)G;G 7% G;T 32% T;T 61%
African ancestry (Southwest US)G;G 5% G;T 28% T;T 67%
Chinese (Denver)G;G <1% G;T 14% T;T 85%
Gujarati IndianG;G 2% G;T 32% T;T 66%
Luhya (Kenya)G;G 4% G;T 28% T;T 68%
Mexican ancestry (Los Angeles)G;G 0% G;T 10% T;T 90%
Maasai (Kenya)G;G 5% G;T 43% T;T 52%
TuscanG;G 1% G;T 13% T;T 86%

Notes

From SNPedia

Notes

A study of 337 subjects with increased risk for type-2 diabetes revealed that magnetic resonance imaging-quantified visceral fat mass was significantly associated (p = .0002) with rs17173608; carriers of a (G) allele displayed lower visceral adipose tissue mass. They were also nominally associated with a lower waist-to-hip ratio (p = .0295). Neither observation held in obese subjects.

Source and license

Adapted from rs17173608 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.