rs17612858(T;T)
Highest risk (~5x higher) for podoconiosis
- Magnitude
- 3.0Important
- Repute
- Bad
- On SNPedia
- rs17612858(T;T)
- Gene
- HLA-DQA1
Other genotypes of rs17612858
Notes
From SNPedia
The presence of the minor allele (T) of this SNP was associated with an increased risk of susceptibility to podoconiosis substantially (odds ratio, 2.44 in the allelic model and 2.19 in the additive model). This is a neglected tropical disease which causes elephantiasis when exposed to volcanic soil. An estimated one-fifth of Ethiopians carry this genotype, increasing their risk for this debilitating disease. http://www.genome.gov/27558535
References
Source and license
Adapted from rs17612858(T;T) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.