rs1799999

A SNP in the PPP1R3A gene on chromosome 7. Its most notable genotype is A;A: insulin resistance

Gene
PPP1R3A
Location
Chr 7113,878,379 (GRCh38)
Highest magnitude
3.0Important
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
29%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. C;CNot ratednormal riskTypical · 0.054% of people
  2. A;CNot ratedNo summary available.Typical · 0.029% of people
  3. A;AMost notableBadinsulin resistanceImportant · 3.017% of people

SNPedia records rs1799999 on the minus strand: (G;G), (G;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageC;C 54% A;C 29% A;A 17%
  • European ancestry (Utah)C;C 88% A;C 12% A;A 0%
  • Han Chinese (Beijing)C;C 7% A;C 44% A;A 49%
  • Japanese (Tokyo)C;C 16% A;C 34% A;A 50%
  • Yoruba (Nigeria)C;C 59% A;C 35% A;A 6%
  • African ancestry (Southwest US)C;C 72% A;C 25% A;A 4%
  • Chinese (Denver)C;C 5% A;C 43% A;A 52%
  • Gujarati IndianC;C 38% A;C 51% A;A 12%
  • Luhya (Kenya)C;C 82% A;C 17% A;A <1%
  • Mexican ancestry (Los Angeles)C;C 59% A;C 33% A;A 9%
  • Maasai (Kenya)C;C 87% A;C 14% A;A 0%
  • TuscanC;C 84% A;C 15% A;A 1%

Other PPP1R3A SNPs

All PPP1R3A SNPs

Source and license

Adapted from rs1799999 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.