rs1800462(G;G)

Incapable of detoxifying certain drugs

Magnitude
3.5Important
Repute
Bad
On SNPedia
rs1800462(C;C)Minus strand
Gene
TPMT

Other genotypes of rs1800462

  1. C;GBaddetoxifying ability of certain drugs may be diminishedWorth knowing · 2.5
  2. C;CGoodnormal for 23andMeTypical · 0.0

All about rs1800462

Notes

From SNPedia

poor drug metabolism of some medications. potentially encoding a variant incapable of detoxifying byproducts of certain antineoplastic and immunosuppressant drugs. http://blog.23andme.com/health-traits/do-you-know-how-youll-respond-to-thiopurine-medications/

Source and license

Adapted from rs1800462(C;C) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.