rs1801968

A SNP in the TOR1A gene on chromosome 9. Its most notable genotype is C;C: common in clinvar

Gene
TOR1A
Location
Chr 9129,818,622 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA
Minor allele frequency
8%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. C;CMost notableGoodcommon in clinvarTypical · 0.084% of people

SNPedia records rs1801968 on the minus strand: (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 10 HapMap populations.

  • AverageC;C 84%
  • European ancestry (Utah)C;C 70%
  • Han Chinese (Beijing)C;C 89%
  • Japanese (Tokyo)C;C 94%
  • Yoruba (Nigeria)C;C 100%
  • African ancestry (Southwest US)C;C 95%
  • Chinese (Denver)C;C 82%
  • Gujarati IndianC;C 63%
  • Mexican ancestry (Los Angeles)C;C 88%
  • Maasai (Kenya)C;C 91%
  • TuscanC;C 69%

Other TOR1A SNPs

All TOR1A SNPs

Notes

From SNPedia

Notes

aka c.646G>C (p.Asp216His or D216H) This variant is reported to be a modifier of the TOR1A variant, rs80358233. Specifically, the 216H allele (c.646C) appears to reduce the odds of developing torsion dystonia in rs80358233(-;GAG) carriers, while the 216D allele appears to increase the odds.,,

Source and license

Adapted from rs1801968 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.