rs180223(T;T)

1.35x increased risk of autoimmune thyroid disease

Magnitude
1.3Minor
Repute
Bad
Frequency
11%Average of 11 populations
On SNPedia
rs180223(T;T)
Gene
TG

Frequency

Share of people with T;T in each HapMap population.

  • European ancestry (Utah)30%
  • Tuscan18%
  • Mexican ancestry (Los Angeles)14%
  • African ancestry (Southwest US)9%
  • Luhya (Kenya)8%
  • Han Chinese (Beijing)8%
  • Gujarati Indian8%
  • Maasai (Kenya)8%
  • Chinese (Denver)7%
  • Yoruba (Nigeria)6%
  • Japanese (Tokyo)4%

Other genotypes of rs180223

  1. G;GGoodreduced risk of autoimmune thyroid disease (0.14x)Worth knowing · 2.049% of people
  2. G;TMost notableBad1.3x to 11.5x Increased risk of autoimmune thyroid diseaseWorth knowing · 2.840% of people

All about rs180223

Notes

From SNPedia

Only the GG variant is protective. See text at rs180223

Source and license

Adapted from rs180223(T;T) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.