rs1805081

A SNP in the NPC1 gene on chromosome 18. Its most notable genotype is A;G.

Gene
NPC1
Location
Chr 1823,560,468 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA
Minor allele frequency
25%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. A;GMost notableNot ratedNo summary available.Typical · 0.00% of people

SNPedia records rs1805081 on the minus strand: (C;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 10 HapMap populations.

  • AverageA;G 0%
  • European ancestry (Utah)A;G 0%
  • Han Chinese (Beijing)A;G 0%
  • Japanese (Tokyo)A;G 0%
  • Yoruba (Nigeria)A;G 0%
  • African ancestry (Southwest US)A;G 0%
  • Chinese (Denver)A;G 0%
  • Gujarati IndianA;G 0%
  • Mexican ancestry (Los Angeles)A;G 0%
  • Maasai (Kenya)A;G 0%
  • TuscanA;G 0%

Other NPC1 SNPs

All NPC1 SNPs

Source and license

Adapted from rs1805081 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.