rs1805126
A SNP in the SCN5A gene on chromosome 3. Its most notable genotype is A;A: common in clinvar
- Gene
- SCN5A
- Location
- Chr 338,550,915 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
- Minor allele frequency
- 49%
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
SNPedia records rs1805126 on the minus strand: (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageA;A 24%
- European ancestry (Utah)A;A 48%
- Han Chinese (Beijing)A;A 20%
- Japanese (Tokyo)A;A 20%
- Yoruba (Nigeria)A;A 8%
- African ancestry (Southwest US)A;A 14%
- Chinese (Denver)A;A 22%
- Gujarati IndianA;A 53%
- Luhya (Kenya)A;A 3%
- Mexican ancestry (Los Angeles)A;A 26%
- Maasai (Kenya)A;A 5%
- TuscanA;A 41%
Related
Other SCN5A SNPs
- rs137854606A;CBrugada SyndromeVery important
- rs137854612C;TBrugada SyndromeVery important
- rs137854615A;GBrugada SyndromeVery important
- rs137854620C;TBrugada SyndromeVery important
- rs199473058C;TBrugada SyndromeVery important
- rs199473083C;TBrugada SyndromeVery important
- rs199473225A;GBrugada SyndromeVery important
- rs199473249C;GBrugada SyndromeVery important
Source and license
Adapted from rs1805126 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.