rs1861046
A SNP in the C1QTNF7 gene on chromosome 4. Its most notable genotype is G;G.
- Gene
- C1QTNF7
- Location
- Chr 415,396,282 (GRCh38)
- Highest magnitude
- 1.0Minor
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
- Minor allele frequency
- 15%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageG;G 71%
- European ancestry (Utah)G;G 93%
- Han Chinese (Beijing)G;G 69%
- Japanese (Tokyo)G;G 60%
- Yoruba (Nigeria)G;G 64%
- African ancestry (Southwest US)G;G 56%
- Chinese (Denver)G;G 73%
- Gujarati IndianG;G 91%
- Luhya (Kenya)G;G 55%
- Mexican ancestry (Los Angeles)G;G 64%
- Maasai (Kenya)G;G 67%
- TuscanG;G 92%
Related
Conditions, medicines and genes
Notes
From SNPedia
Show notes, about 140 words
G;G
Conduct disorder (CD) is one of the most prevalent childhood psychiatric conditions, and is associated with a number of serious concomitant and future problems. CD symptomatology is known to have a considerable genetic component, with heritability estimates in the range of 50%. Four SNPs reached genome-wide significance with CD symptom count, based on P < 5x10^-8 Two of these SNPs (rs16891867 and rs1861046) were in the gene C1QTNF7 (C1q and tumor necrosis factor-related protein 7). These SNPs were in high LD (r^2=0.97). The other top two SNPs meeting genome-wide significance were intergenic and located on chromosomes 11 and 13. Alleles A/G were found to be associated with CD symptom count or CD case status. downstate.edu
Source and license
Adapted from rs1861046 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.