rs1921

A SNP in the ISG15 gene on chromosome 1. Its most notable genotype is G;G: common in clinvar

Gene
ISG15
Location
Chr 11,014,228 (GRCh38)
Highest magnitude
0.0Typical
Tested on
Not on consumer chips
Minor allele frequency
34%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. G;GMost notableGoodcommon in clinvarTypical · 0.050% of people

On SNPedia: (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 9 HapMap populations.

  • AverageG;G 50%
  • Han Chinese (Beijing)G;G 63%
  • Japanese (Tokyo)G;G 63%
  • Yoruba (Nigeria)G;G 34%
  • Chinese (Denver)G;G 70%
  • Gujarati IndianG;G 48%
  • Luhya (Kenya)G;G 33%
  • Mexican ancestry (Los Angeles)G;G 52%
  • Maasai (Kenya)G;G 52%
  • TuscanG;G 36%

Other ISG15 SNPs

All ISG15 SNPs

Source and license

Adapted from rs1921 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.