rs198846

A SNP in the HIST1H1T gene on chromosome 6. Its most notable genotype is A;A.

Gene
HIST1H1T
Location
Chr 626,107,235 (GRCh38)
Highest magnitude
3.0Important
Tested on
23andMe, AncestryDNA
Minor allele frequency
12%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AMost notableNot ratedNo summary available.Important · 3.01% of people
  2. A;GNot ratedNo summary available.Worth knowing · 2.020% of people
  3. G;GNot ratedNo summary available.Typical · 0.079% of people

On SNPedia: (A;A), (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageA;A 1% A;G 20% G;G 79%
  • European ancestry (Utah)A;A <1% A;G 29% G;G 70%
  • Han Chinese (Beijing)A;A 0% A;G 7% G;G 93%
  • Japanese (Tokyo)A;A 0% A;G 7% G;G 93%
  • Yoruba (Nigeria)A;A 2% A;G 35% G;G 63%
  • African ancestry (Southwest US)A;A 4% A;G 16% G;G 81%
  • Chinese (Denver)A;A 0% A;G 6% G;G 95%
  • Gujarati IndianA;A 0% A;G 17% G;G 83%
  • Luhya (Kenya)A;A 3% A;G 23% G;G 75%
  • Mexican ancestry (Los Angeles)A;A 0% A;G 28% G;G 72%
  • Maasai (Kenya)A;A 2% A;G 22% G;G 76%
  • TuscanA;A 4% A;G 27% G;G 70%

Source and license

Adapted from rs198846 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.