rs2070995

A SNP in the KCNJ6 gene on chromosome 21. Its most notable genotype is C;T.

Gene
KCNJ6
Location
Chr 2137,714,662 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe
Minor allele frequency
20%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. C;TMost notableNot ratedNo summary available.Typical · 0.027% of people

SNPedia records rs2070995 on the minus strand: (A;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageC;T 27%
  • European ancestry (Utah)C;T 29%
  • Han Chinese (Beijing)C;T 43%
  • Japanese (Tokyo)C;T 50%
  • Yoruba (Nigeria)C;T <1%
  • African ancestry (Southwest US)C;T 4%
  • Chinese (Denver)C;T 58%
  • Gujarati IndianC;T 30%
  • Luhya (Kenya)C;T 2%
  • Mexican ancestry (Los Angeles)C;T 39%
  • Maasai (Kenya)C;T 3%
  • TuscanC;T 34%

Notes

From SNPedia

Notes

Epistatic interaction of CREB1 and KCNJ6 on rumination and negative emotionality. Effect sizes in experimental pain produced by gender, genetic variants and sensitization procedures.

Source and license

Adapted from rs2070995 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.