rs2073724

A SNP in the TCF19 gene on chromosome 6. Its most notable genotype is C;T: Higher (1.9x) risk for COVID-19 illness being severe

Gene
TCF19
Location
Chr 631,161,930 (GRCh38)
Highest magnitude
1.9Minor
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
9%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;CGoodcommon on affy axiom dataTypical · 0.086% of people
  2. C;TMost notableBadHigher (1.9x) risk for COVID-19 illness being severeMinor · 1.913% of people

On SNPedia: (C;C), (C;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageC;C 86% C;T 13%
  • European ancestry (Utah)C;C 87% C;T 12%
  • Han Chinese (Beijing)C;C 86% C;T 12%
  • Japanese (Tokyo)C;C 96% C;T 4%
  • Yoruba (Nigeria)C;C 82% C;T 18%
  • African ancestry (Southwest US)C;C 93% C;T 7%
  • Chinese (Denver)C;C 92% C;T 8%
  • Gujarati IndianC;C 81% C;T 18%
  • Luhya (Kenya)C;C 90% C;T 10%
  • Mexican ancestry (Los Angeles)C;C 72% C;T 26%
  • Maasai (Kenya)C;C 96% C;T 4%
  • TuscanC;C 75% C;T 24%

Notes

From SNPedia

Notes

Distinct genetic loci control plasma HIV-RNA and cellular HIV-DNA levels in HIV-1 infection: the ANRS Genome Wide Association 01 study.

C;T

see rs143334143

Source and license

Adapted from rs2073724 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.