rs2075577

A SNP in the UCP3 gene on chromosome 11. Its most notable genotype is G;G: Larger stomach volume, does not get full as easily as T allele carriers

Gene
UCP3
Location
Chr 1174,004,497 (GRCh38)
Highest magnitude
2.1Worth knowing
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
40%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. G;GMost notableNot ratedLarger stomach volume, does not get full as easily as T allele carriersWorth knowing · 2.118% of people
  2. A;GNot ratedAverage stomach volume, gets as full as the average personMinor · 1.542% of people
  3. A;ANot ratedSmaller stomach volume, gets full quickerWorth knowing · 2.140% of people

SNPedia records rs2075577 on the minus strand: (C;C), (C;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageG;G 18% A;G 42% A;A 40%
  • European ancestry (Utah)G;G 19% A;G 50% A;A 32%
  • Han Chinese (Beijing)G;G 34% A;G 42% A;A 24%
  • Japanese (Tokyo)G;G 20% A;G 50% A;A 30%
  • Yoruba (Nigeria)G;G 2% A;G 24% A;A 74%
  • African ancestry (Southwest US)G;G 4% A;G 40% A;A 56%
  • Chinese (Denver)G;G 29% A;G 57% A;A 14%
  • Gujarati IndianG;G 36% A;G 43% A;A 22%
  • Luhya (Kenya)G;G <1% A;G 25% A;A 75%
  • Mexican ancestry (Los Angeles)G;G 26% A;G 52% A;A 22%
  • Maasai (Kenya)G;G 4% A;G 31% A;A 65%
  • TuscanG;G 24% A;G 53% A;A 24%

Other UCP3 SNPs

All UCP3 SNPs

Source and license

Adapted from rs2075577 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.