rs210138

A SNP in the BAK1 gene on chromosome 6. Its most notable genotype is G;G: Testicular Cancer

Gene
BAK1
Location
Chr 633,574,761 (GRCh38)
Highest magnitude
2.7Worth knowing
Tested on
23andMe, AncestryDNA
Minor allele frequency
24%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AGoodcommon in complete genomicsTypical · 0.056% of people
  2. G;GMost notableBadTesticular CancerWorth knowing · 2.710% of people

On SNPedia: (A;A), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageA;A 56% G;G 10%
  • European ancestry (Utah)A;A 67% G;G 4%
  • Han Chinese (Beijing)A;A 37% G;G 23%
  • Japanese (Tokyo)A;A 31% G;G 17%
  • Yoruba (Nigeria)A;A 85% G;G <1%
  • African ancestry (Southwest US)A;A 81% G;G 2%
  • Chinese (Denver)A;A 24% G;G 24%
  • Gujarati IndianA;A 36% G;G 21%
  • Luhya (Kenya)A;A 66% G;G 2%
  • Mexican ancestry (Los Angeles)A;A 55% G;G 10%
  • Maasai (Kenya)A;A 70% G;G 5%
  • TuscanA;A 71% G;G 3%

Conditions, medicines and genes

Notes

From SNPedia

Notes

23andMe blog each rs210138(G) was found to increase the odds of testicular cancer by 1.5x

G;G

May increase odds 3X (1.5X for each G)

Source and license

Adapted from rs210138 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.