rs2157249
A SNP in the APOL2 gene on chromosome 22. Its most notable genotype is T;T: common in complete genomics
- Gene
- APOL2
- Location
- Chr 2236,234,993 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
- Minor allele frequency
- 19%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 10 HapMap populations.
- AverageT;T 67%
- European ancestry (Utah)T;T 46%
- Han Chinese (Beijing)T;T 100%
- Japanese (Tokyo)T;T 100%
- Yoruba (Nigeria)T;T 73%
- African ancestry (Southwest US)T;T 61%
- Gujarati IndianT;T 62%
- Luhya (Kenya)T;T 74%
- Mexican ancestry (Los Angeles)T;T 64%
- Maasai (Kenya)T;T 48%
- TuscanT;T 42%
Related
Notes
From SNPedia
Notes
rs9610449 schizophrenia (377 families, 1161 genotyped members and 647 genotyped affected in total) rs9610449 and rs6000200 associated with risk for schizophrenia in African-Americans. In the combined (AA and EA) sample, two SNPs, rs2003813 and rs2157249
Source and license
Adapted from rs2157249 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.