rs216293
A SNP in the VWF gene on chromosome 12. Its most notable genotype is G;G: common in clinvar
- Gene
- VWF
- Location
- Chr 126,044,493 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, FamilyTreeDNA
- Minor allele frequency
- 47%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageG;G 26%
- European ancestry (Utah)G;G 21%
- Han Chinese (Beijing)G;G 6%
- Japanese (Tokyo)G;G 13%
- Yoruba (Nigeria)G;G 60%
- African ancestry (Southwest US)G;G 61%
- Chinese (Denver)G;G 4%
- Gujarati IndianG;G 9%
- Luhya (Kenya)G;G 56%
- Mexican ancestry (Los Angeles)G;G 7%
- Maasai (Kenya)G;G 30%
- TuscanG;G 18%
Related
Other VWF SNPs
- rs41276738T;TVon Willebrand disease, type 1Very important
- rs61748477A;AVon Willebrand disease, type 2NVery important
- rs61748478C;CVon Willebrand disease, type 2NVery important
- rs61748497G;GVon Willebrand disease, type 2NVery important
- rs61750584G;GVon Willebrand disease, type 2AVery important
- rs61750595A;Alikely miscall in Ancestry V2.0 datasets; otherwise, Von Willebrand disease, type 3Very important
- rs61750612A;AVon Willebrand disease, type 3Very important
- rs61750630A;AVon Willebrand disease, type 3Very important
Source and license
Adapted from rs216293 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.