rs2227852

A SNP in the DRD5 gene on chromosome 4. Its most notable genotype is A;A.

Gene
DRD5
Location
Chr 49,782,741 (GRCh38)
Highest magnitude
1.0Minor
Tested on
23andMe

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AMost notableNot ratedNo summary available.Minor · 1.025% of people
  2. G;GNot ratedcommon for caucasians, despite hapmapTypical · 0.075% of people

On SNPedia: (A;A), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 4 HapMap populations.

  • AverageA;A 25% G;G 75%
  • European ancestry (Utah)A;A 99% G;G 0%
  • Han Chinese (Beijing)A;A 0% G;G 100%
  • Japanese (Tokyo)A;A 0% G;G 100%
  • Yoruba (Nigeria)A;A 0% G;G 100%

Notes

From SNPedia

Notes

The role of geography in human adaptation.

A;A

HapMap claims this genotype is extremely rare, but evidence from users suggests that the A allele is normal in caucasians

Source and license

Adapted from rs2227852 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.