rs2227956

A SNP in the HSPA1L gene on chromosome 6. Its most notable genotype is A;A.

Gene
HSPA1L
Location
Chr 631,810,495 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
12%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. A;AMost notableNot ratedNo summary available.Typical · 0.078% of people

SNPedia records rs2227956 on the minus strand: (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageA;A 78%
  • European ancestry (Utah)A;A 58%
  • Han Chinese (Beijing)A;A 61%
  • Japanese (Tokyo)A;A 83%
  • Yoruba (Nigeria)A;A 100%
  • African ancestry (Southwest US)A;A 93%
  • Chinese (Denver)A;A 63%
  • Gujarati IndianA;A 63%
  • Luhya (Kenya)A;A 90%
  • Mexican ancestry (Los Angeles)A;A 90%
  • Maasai (Kenya)A;A 72%
  • TuscanA;A 80%

Conditions, medicines and genes

Notes

From SNPedia

Notes

rs2227956 in HSP70-hom, resulted in a significant association with noise-induced hearing loss

Source and license

Adapted from rs2227956 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.