rs2228093

A SNP in the ALDH1B1 gene on chromosome 9. Its most notable genotype is T;T: Associated with alcohol-induced hypersensitivity reactions

Gene
ALDH1B1
Location
Chr 938,396,005 (GRCh38)
Highest magnitude
3.0Important
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
22%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;CGoodcommon in clinvarTypical · 0.059% of people
  2. T;TMost notableBadAssociated with alcohol-induced hypersensitivity reactionsImportant · 3.07% of people

On SNPedia: (C;C), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageC;C 59% T;T 7%
  • European ancestry (Utah)C;C 70% T;T 2%
  • Han Chinese (Beijing)C;C 34% T;T 15%
  • Japanese (Tokyo)C;C 40% T;T 11%
  • Yoruba (Nigeria)C;C 81% T;T <1%
  • African ancestry (Southwest US)C;C 77% T;T 5%
  • Chinese (Denver)C;C 31% T;T 19%
  • Gujarati IndianC;C 51% T;T 6%
  • Luhya (Kenya)C;C 86% T;T <1%
  • Mexican ancestry (Los Angeles)C;C 36% T;T 14%
  • Maasai (Kenya)C;C 76% T;T 1%
  • TuscanC;C 73% T;T 1%

Notes

From SNPedia

Notes

T;T

Found in both Asian and Caucasian populations.

Source and license

Adapted from rs2228093 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.