rs2228638

A SNP in the NRP1 gene on chromosome 10. Its most notable genotype is C;C.

Gene
NRP1
Location
Chr 1033,186,354 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
10%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. C;CMost notableGoodNo summary available.Typical · 0.082% of people

SNPedia records rs2228638 on the minus strand: (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 10 HapMap populations.

  • AverageC;C 82%
  • European ancestry (Utah)C;C 74%
  • Han Chinese (Beijing)C;C 79%
  • Japanese (Tokyo)C;C 75%
  • Yoruba (Nigeria)C;C 100%
  • African ancestry (Southwest US)C;C 97%
  • Chinese (Denver)C;C 76%
  • Gujarati IndianC;C 73%
  • Mexican ancestry (Los Angeles)C;C 64%
  • Maasai (Kenya)C;C 99%
  • TuscanC;C 87%

Source and license

Adapted from rs2228638 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.