rs2230600

A SNP in the PTPN13 gene on chromosome 4. Its most notable genotype is G;G.

Gene
PTPN13
Location
Chr 486,769,845 (GRCh38)
Highest magnitude
1.9Minor
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
19%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. G;GMost notableNot ratedNo summary available.Minor · 1.94% of people

On SNPedia: (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageG;G 4%
  • European ancestry (Utah)G;G 6%
  • Han Chinese (Beijing)G;G 6%
  • Japanese (Tokyo)G;G 12%
  • Yoruba (Nigeria)G;G 0%
  • African ancestry (Southwest US)G;G 0%
  • Chinese (Denver)G;G 7%
  • Gujarati IndianG;G 2%
  • Luhya (Kenya)G;G 0%
  • Mexican ancestry (Los Angeles)G;G 11%
  • Maasai (Kenya)G;G 0%
  • TuscanG;G 0%

Notes

From SNPedia

Notes

rs2230600 We found that a significantly increased squamous cell carcinoma of the head and neck risk was associated with the c.4566 I1522M (G;G) genotype [odds ratio (OR), 1.89; 95% confidence interval (CI), 1.27-2.79

Source and license

Adapted from rs2230600 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.