rs2234671

A SNP in the CXCR1 gene on chromosome 2. Its most notable genotype is C;C: common in complete genomics

Gene
CXCR1
Location
Chr 2218,164,385 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe
Minor allele frequency
11%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. C;CMost notableGoodcommon in complete genomicsTypical · 0.075% of people

SNPedia records rs2234671 on the minus strand: (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 4 HapMap populations.

  • AverageC;C 75%
  • European ancestry (Utah)C;C 90%
  • Han Chinese (Beijing)C;C 80%
  • Japanese (Tokyo)C;C 80%
  • Yoruba (Nigeria)C;C 50%

Other CXCR1 SNPs

All CXCR1 SNPs

Notes

From SNPedia

Show notes, about 170 words

Impact of IL8 and IL8-receptor alpha polymorphisms on the genetics of bronchial asthma and severe RSV infections. Polymorphisms in chemokine receptor genes and susceptibility to Kawasaki disease. Optimization of candidate-gene SNP-genotyping by flexible oligonucleotide microarrays; analyzing variations in immune regulator genes of hay-fever samples. Variants in inflammation genes and the risk of biliary tract cancers and stones: a population-based study in China. Genetic variation of the human urinary tract innate immune response and asymptomatic bacteriuria in women. CXCR1 and SLC11A1 polymorphisms affect susceptibility to cutaneous leishmaniasis in Brazil: a case-control and family-based study. Genetic variants in inflammation-related genes are associated with radiation-induced toxicity following treatment for non-small cell lung cancer. Pharmacogenetic angiogenesis profiling for first-line Bevacizumab plus oxaliplatin-based chemotherapy in patients with metastatic colorectal cancer.

Source and license

Adapted from rs2234671 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.