rs2235749

A SNP in the PDYN gene on chromosome 20. Its most notable genotype is G;G: common in clinvar

Gene
PDYN
Location
Chr 201,979,293 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
48%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. G;GMost notableGoodcommon in clinvarTypical · 0.025% of people

On SNPedia: (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageG;G 25%
  • European ancestry (Utah)G;G 55%
  • Han Chinese (Beijing)G;G 3%
  • Japanese (Tokyo)G;G 6%
  • Yoruba (Nigeria)G;G 23%
  • African ancestry (Southwest US)G;G 21%
  • Chinese (Denver)G;G <1%
  • Gujarati IndianG;G 20%
  • Luhya (Kenya)G;G 22%
  • Mexican ancestry (Los Angeles)G;G 40%
  • Maasai (Kenya)G;G 25%
  • TuscanG;G 54%

Other PDYN SNPs

All PDYN SNPs

Notes

From SNPedia

Notes

In Caucasians, we found point-wise significant associations of 3' UTR SNPs (rs910080, rs910079, and rs2235749) with cocaine dependence and cocaine/alcohol codependence.

Source and license

Adapted from rs2235749 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.