rs2236851
A SNP in the RUNX3 gene on chromosome 1. Its most notable genotype is C;C: common in complete genomics
- Gene
- RUNX3
- Location
- Chr 124,917,063 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, FamilyTreeDNA
- Minor allele frequency
- 11%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 4 HapMap populations.
- AverageC;C 84%
- European ancestry (Utah)C;C 73%
- Han Chinese (Beijing)C;C 85%
- Japanese (Tokyo)C;C 80%
- Yoruba (Nigeria)C;C 100%
Notes
From SNPedia
Notes
significant association between rs2236851 and ulcerative colitis (OR 1.61; 95% confidence interval [CI] 1.11-2.32, P = 0.020). Chromatin immunoprecipitation and association study revealed a possible role of Runt-related transcription factor 3 in the ulcerative colitis of Chinese population.
Source and license
Adapted from rs2236851 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.