rs2238472

A SNP in the ABCC6 gene on chromosome 16. Its most notable genotype is T;T: most likely a benign polymorphism

Gene
ABCC6
Location
Chr 1616,157,742 (GRCh38)
Highest magnitude
1.0Minor
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
19%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. T;TMost notableGoodmost likely a benign polymorphismMinor · 1.03% of people
  2. C;TGoodmost likely a benign polymorphismMinor · 1.023% of people
  3. C;CGoodcommon in clinvarTypical · 0.074% of people

SNPedia records rs2238472 on the minus strand: (A;A), (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageT;T 3% C;T 23% C;C 74%
  • European ancestry (Utah)T;T 8% C;T 31% C;C 61%
  • Han Chinese (Beijing)T;T <1% C;T 19% C;C 80%
  • Japanese (Tokyo)T;T 4% C;T 27% C;C 68%
  • Yoruba (Nigeria)T;T <1% C;T 14% C;C 85%
  • African ancestry (Southwest US)T;T 2% C;T 19% C;C 79%
  • Chinese (Denver)T;T <1% C;T 25% C;C 74%
  • Gujarati IndianT;T 3% C;T 35% C;C 62%
  • Luhya (Kenya)T;T 0% C;T 13% C;C 87%
  • Mexican ancestry (Los Angeles)T;T 7% C;T 31% C;C 62%
  • Maasai (Kenya)T;T <1% C;T 8% C;C 92%
  • TuscanT;T 8% C;T 31% C;C 61%

Other ABCC6 SNPs

All ABCC6 SNPs

Source and license

Adapted from rs2238472 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.