rs2240308

A SNP in the AXIN2 gene on chromosome 17. Its most notable genotype is A;A.

Gene
AXIN2
Location
Chr 1765,558,473 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA
Minor allele frequency
35%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AMost notableNot ratedNo summary available.Typical · 0.011% of people
  2. G;GGoodcommon in clinvarTypical · 0.054% of people

On SNPedia: (A;A), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageA;A 11% G;G 54%
  • European ancestry (Utah)A;A 26% G;G 29%
  • Han Chinese (Beijing)A;A 13% G;G 44%
  • Japanese (Tokyo)A;A 9% G;G 49%
  • Yoruba (Nigeria)A;A <1% G;G 96%
  • African ancestry (Southwest US)A;A 9% G;G 65%
  • Chinese (Denver)A;A 8% G;G 44%
  • Gujarati IndianA;A 16% G;G 39%
  • Luhya (Kenya)A;A <1% G;G 84%
  • Mexican ancestry (Los Angeles)A;A 19% G;G 19%
  • Maasai (Kenya)A;A <1% G;G 85%
  • TuscanA;A 17% G;G 36%

Other AXIN2 SNPs

All AXIN2 SNPs

Notes

From SNPedia

Notes

AXIN2 and CDH1 polymorphisms, tooth agenesis, and oral clefts. Axis inhibition protein 2 (AXIN2) polymorphisms and tooth agenesis.

Source and license

Adapted from rs2240308 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.