rs2251219(C;C)
Lower bipolar disorder risk?
- Magnitude
- 0.0Typical
- Repute
- Good
- Frequency
- 15%Average of 11 populations
- On SNPedia
- rs2251219(G;G)Minus strand
- Gene
- PBRM1
Frequency
Share of people with C;C in each HapMap population.
- Mexican ancestry (Los Angeles)41%
- Tuscan30%
- Japanese (Tokyo)26%
- Han Chinese (Beijing)18%
- Chinese (Denver)16%
- European ancestry (Utah)11%
- Gujarati Indian8%
- African ancestry (Southwest US)7%
- Luhya (Kenya)5%
- Yoruba (Nigeria)1%
- Maasai (Kenya)<1%
Other genotypes of rs2251219
Notes
From SNPedia
The C-allele of rs2251219 was significantly under-represented in bipolar disorder cases compared to controls (p=0.002, OR = 0.57; Table 2), replicating our main meta-analysis result.
References
Source and license
Adapted from rs2251219(G;G) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.