rs2253319

A SNP in the RUNX1 gene on chromosome 21. Its most notable genotype is C;T: common in complete genomics

Gene
RUNX1
Location
Chr 2134,815,749 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
41%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;TMost notableGoodcommon in complete genomicsTypical · 0.047% of people

On SNPedia: (C;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageC;T 47%
  • European ancestry (Utah)C;T 43%
  • Han Chinese (Beijing)C;T 46%
  • Japanese (Tokyo)C;T 51%
  • Yoruba (Nigeria)C;T 50%
  • African ancestry (Southwest US)C;T 47%
  • Chinese (Denver)C;T 55%
  • Gujarati IndianC;T 54%
  • Luhya (Kenya)C;T 43%
  • Mexican ancestry (Los Angeles)C;T 31%
  • Maasai (Kenya)C;T 51%
  • TuscanC;T 49%

Source and license

Adapted from rs2253319 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.