rs227092
A SNP in the ATM gene on chromosome 11. Its most notable genotype is G;G: common in clinvar
- Gene
- ATM
- Location
- Chr 11108,366,056 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe
- Minor allele frequency
- 49%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageG;G 33%
- European ancestry (Utah)G;G 23%
- Han Chinese (Beijing)G;G 34%
- Japanese (Tokyo)G;G 35%
- Yoruba (Nigeria)G;G 42%
- African ancestry (Southwest US)G;G 33%
- Chinese (Denver)G;G 28%
- Gujarati IndianG;G 12%
- Luhya (Kenya)G;G 58%
- Mexican ancestry (Los Angeles)G;G 25%
- Maasai (Kenya)G;G 54%
- TuscanG;G 16%
Related
Other ATM SNPs
- rs147557621G;TBreast cancer associated mutationVery important
- rs200976093C;TBreast cancer associated mutationVery important
- rs376170600C;GBreast cancer associated mutationVery important
- rs376603775C;TBreast cancer associated mutationVery important
- rs529296539C;GBreast cancer associated mutationVery important
- rs587776551A;GBreast cancer associated mutationVery important
- rs587778080C;TBreast cancer associated mutationVery important
- rs587779813A;GBreast cancer associated mutationVery important
Notes
From SNPedia
Notes
reduced cytokinesis-block micronucleus (CBMN) frequency among workers exposed to polycyclic aromatic hydrocarbons *rs600931(G;G) *rs189037(G;G) *rs624366(G;G) *rs227092(G;G)
Source and license
Adapted from rs227092 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.