rs227368

A SNP in the MANBA gene on chromosome 4. Its most notable genotype is A;G.

Gene
MANBA
Location
Chr 4102,690,688 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
40%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. A;GMost notableNot ratedNo summary available.Typical · 0.00% of people
  2. C;CGoodcommon in clinvarTypical · 0.045% of people

SNPedia records rs227368 on the minus strand: (C;T), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageA;G 0% C;C 45%
  • European ancestry (Utah)A;G 0% C;C 24%
  • Han Chinese (Beijing)A;G 0% C;C 23%
  • Japanese (Tokyo)A;G 0% C;C 20%
  • Yoruba (Nigeria)A;G 0% C;C 78%
  • African ancestry (Southwest US)A;G 0% C;C 72%
  • Chinese (Denver)A;G 0% C;C 25%
  • Gujarati IndianA;G 0% C;C 26%
  • Luhya (Kenya)A;G 0% C;C 76%
  • Mexican ancestry (Los Angeles)A;G 0% C;C 50%
  • Maasai (Kenya)A;G 0% C;C 72%
  • TuscanA;G 0% C;C 25%

Other MANBA SNPs

All MANBA SNPs

Source and license

Adapted from rs227368 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.