rs2274223(A;G)

1.5x increased risk for stomach & esophageal cancer (seen in Han Chinese)

Magnitude
2.0Worth knowing
Repute
Bad
Frequency
42%Average of 11 populations
On SNPedia
rs2274223(A;G)
Gene
PLCE1

Frequency

Share of people with A;G in each HapMap population.

  • Maasai (Kenya)53%
  • European ancestry (Utah)50%
  • African ancestry (Southwest US)49%
  • Yoruba (Nigeria)48%
  • Luhya (Kenya)48%
  • Tuscan43%
  • Gujarati Indian41%
  • Han Chinese (Beijing)36%
  • Chinese (Denver)34%
  • Japanese (Tokyo)32%
  • Mexican ancestry (Los Angeles)31%

Other genotypes of rs2274223

  1. A;AGoodnormalTypical · 0.048% of people
  2. G;GMost notableBad1.9x increased risk for stomach & esophageal cancer (seen in Han Chinese)Worth knowing · 2.410% of people

All about rs2274223

Source and license

Adapted from rs2274223(A;G) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.